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Ethyl Lauroyl Arginate HCl 60372-77-2 Healthy Food Additives
Product Details:
| Place of Origin: | CHINA |
| Brand Name: | AK BIOTECH |
| Certification: | COA |
| Model Number: | 60372-77-2 |
Payment & Shipping Terms:
| Minimum Order Quantity: | 1G |
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| Price: | $1-100/G |
| Packaging Details: | 1g to 25kg, Please notify us in advance if request for special packing. |
| Delivery Time: | 1-7 work days |
| Payment Terms: | T/T |
| Supply Ability: | 1000KG |
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Detail Information |
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| Highlight: | 60372-77-2 Healthy Food Additives,Ethyl lauroyl arginate HCl 60372-77-2,Ethyl Lauroyl Arginate HCl 60372-77-2 |
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Product Description
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Name: |
Ethyl lauroyl arginate HCl |
| CAS No: | 60372-77-2 |
| M.W: | 421.02 |
| Appearance: | White powder |
| Purity: | 97% |
| Product No: | AK0032 |
| Synonyms: | ELA;LAE;N(alpha)-Lauroyl-arginine Ethyl Ester HCl |
| Product description: |
Ethyl lauroyl arginate HCl (60372-77-2)has achieved tonnage scale supply to well-known enterprises at home and abroad, the product quality has been highly praised, superior to similar products in the market, and provides good support for the quality stability of downstream products. Ethyl lauroyl arginate HCl (60372-77-2)is our company's standing stock products. Welcome new and old customers to inquire. |
| Similar products: |
N(alpha)-lauroyl-arginine ethyl ester CAS:48076-74-0 N(alpha)-lauroyl-L-arginine ethyl ester acetate CAS:92071-96-0 N(alpha)-lauroyl-L-arginine ethyl ester laurate CAS:1193347-26-0 N(alpha)-lauroyl-arginine ethyl ester 3-picolinate AK0293 N(alpha)-lauroyl-arginine ethyl ester tartrate AK0292 N(alpha)-lauroyl-L-arginine ethyl ester oxalate AK0291 |
| Purpose : | Ethyl lauroyl arginate HCl is a bacteriostatic agent used in food. It is also used as a preservative in cosmetic additives. Lauroyl arginine ethyl ester hydrochloride has good antibacterial effect on Gram-positive bacteria, Gram-negative bacteria, pathogens, yeast and molds, and the minimum inhibitory concentration is 8 μ G / ml, the minimum inhibitory concentration for pathogenic Escherichia coli, beer yeast, Aspergillus niger and Listeria is 32 μ G / ml, is a safe and efficient preservative. |
| Other: | ELA has been developed by us since 2015, and its sales volume continues to rise. It is supplied to many countries around the world as food and cosmetic additives. Domestic regulations approved the entry into the catalogue of cosmetic additives in 2021. At the same time, we have ELA related patents under application. In order to assist the research, we also develop non salt and other salt forms of related series of products |
Product parameters:
| Items | Inspection Standard |
| Appearance | White powder |
| TLC | ≥95.00% |
| Purity(HPLC) | ≥97.00% |
| Lauric acid≤5% | |
| Ethyl laurate≤3% | |
| L-Arginine.HCl≤1% | |
| Ethyl arginine.2HCl≤1% | |
| N-Lauroyl-L-arginine≤3% | |
| Solubility | Freely soluble in water, ethanol, propylene glycol and glycerol |
| Melting Point | 50-62℃ |
| Water Content) | ≤5.0% |
| PH | 3.0-5.0(1% aqueous solution) |
| Assay(AgNO3) | 90.0%～100.0% |
| Lead | ≤1mg/Kg |
| Arsenic | ≤3mg/Kg |
| Cadmium | ≤1mg/Kg |
| Mercury | ≤1mg/Kg |
In September 2005, the US FDA issued a statement stating that there is no problem with the use of lauroyl arginine ethyl ester hydrochloride. The notice: lauroyl arginine ethyl ester is GRAS (announcement number GRN 000164) for use in the designated The category of antibacterial agents is as high as 225mg/kg.
On December 16, 2013, Health Canada's Pest Management Agency (PMRA) issued a proposal for Ethyl Lauroyl Arginate as a variety of standardized and non-standardized food preservatives.
In 2014, the European Union issued Commission Regulation (EU) No 506/2014, approving ethyl lauroyl arginine as a preservative for heat-processed meat products (except emulsified sausage, smoked sausage and liver paste), the maximum use amount is 160mg /kg.
Australia has also published the usage standard of ethyl lauroyl arginine HCl in Food Standards Australia New Zealand (FSANZ), Food Technology Report-Application A1015.
On July 12, 2016, the European Union revised the Annex V of the Cosmetic Regulation (EC) No 1223/2009 again, adding that it allowed lauroyl arginine ethyl ester hydrochloride to be used as a preservative in mouthwashes with a concentration of 0.15% w Below /w.
ELA can be used as a preservative and widely used in the food and cosmetic industries. It can also be used in pesticides, coatings and other fields as an antiseptic and antibacterial agent.
The new food preservative made of ELA as raw material and food-grade solvent as auxiliary material has a wide range of antibacterial activity, can effectively inhibit Gram-positive, Gram-negative bacteria, mold and yeast, and can quickly in the digestive tract Metabolism is an excellent new preservative product.
The detailed data of MIC for Gram-positive bacteria, Gram-negative bacteria, pathogens, yeasts and molds are described in Table 1 to Table 4 below.
Table 1 The minimum inhibitory concentration of LAE on Gram-positive bacteria
|
Gram-positive bacteria |
Minimum inhibitory concentration (Ug/ml) |
| Alicyclic acid bacillus DSMZ 14558 | 8 |
| Arthrobacter oxidans ATCC 8010 Bacillus cereus | 64 |
| ATCC 11778 Bacillus subtilis | 32 |
| 6633 Clostridium botulinum ATCC 19397 | 16 |
| Clostridium perfringens ATCC 77454 | 64 |
| Clostridium perfringens ATCC 12917 | 16 |
| Lactobacillus flexus ATCC 25601 Debel | 16 |
| Lactobacillus plantarum ATCC 25302 Lactobacillus plantarum | 16 |
| Acid bacillus ATCC 25302 Lactobacillus plantarum | 16 |
| ATCC 8014 Listeria monocytogenes | 16 |
| B4/971 Listeria ATCC 15313 Intestinal system | 16 |
| Leuconostoc membranaceus ATCC 19255 Garcinia Microspheres | 8 |
| Bacteria ATCC 9631 | 32 |
| Mycobacterium phlei ATCC 41423 | 32 |
| Staphylococcus aureus ATCC 6538 | 128 |
Table 2 The minimum inhibitory concentration of LAE on Gram-negative bacteria
| Gram-positive bacteria |
Minimum inhibitory concentration (Ug/ml) |
| Alcaligenes faecalis ATCC 8750 | 64 |
| Bordetella bronchiseptica ATCC 4617 | 128 |
| Campylobacter jejuni ATCC 2942 | 8 |
| Campylobacter jejuni HC2 Citrobacter freundii ATCC 22636 | 64 |
| Enterobacter aerogenes ATCC 13048 | 32 |
| Enterococcus faecalis ATCC 27285 | 4 |
| Enterobacter sakazakii ATCC 29544 | 32 |
| Escherichia coli ATCC 35150 | 32 |
| Escherichia coli ATCC 8739 | 32 |
| Klebsiella pneumoniae ATCC 4352 | 32 |
| Proteus CECT 170 | 32 |
| Pseudomonas aeruginosa ATCC 9027 | 32 |
| High-yielding siderophore Pseudomonas fluorescens ATCC 13430 | 32 |
| Salmonella cholerae ATCC 13076 | 8 |
| Salmonella typhimurium ATCC 14028 | 32 |
| Shigella dysenteria ATCC 13313 | 8 |
| Serratia decolorized ATCC 10759 | 32 |
| Yersinia enterocolitica ATCC 27729 | 16 |
| Vibrio parahaemolyticus ATCC 17802 | 128 |
Table 3 The minimum inhibitory concentration of LAE on yeast
| Yeast |
Minimum inhibitory concentration (Ug/ml) |
| Candida albicans ATCC 10231 | 16 |
| Crimson Yeast CECT 1158 | 16 |
| Beer Yeast ATCC 9763 | 32 |
Table 4 The minimum inhibitory concentration of LAE on mold
| Mold | Minimum inhibitory concentration (Ug/ml) |
| Aspergillus niger ATCC 14604 | 32 |
| Aureobasidium pullulans ATCC 9348 | 16 |
| Gliocladium virens ATCC 4645 | 32 |
| Chitocin ATCC 6205 | 16 |
| Penicillium chrysogenum ATCC 9480 | 128 |
| Penicillium funiculosum CECT 2914 | 16 |
● The safety of ELA
According to research, ELA does not affect the reproduction and development of organisms, nor does it have any mutagenic and disruptive effects. The maximum non-effect dose is 15000mg/Kg. Acute toxicity study results are that the oral LD50 and skin contact LD50 are both greater than 2000mg/Kg; the maximum non-effect dose obtained from the subchronic toxicity study is: 15000mg/Kg; the chronic toxicity study result shows that the maximum non-effect dose is 6000mg/Kg.
● Usage and dosage
(1) Irregular non-alcoholic water drinks, vegetable juices and fruit juice products, water-based flavored drinks, high-energy drinks, soft drinks, etc., usage amount: 50-100mg/Kg.
(2) Cheese, fruits and vegetables, cereal products, semi-processed fish and fish products, processed meat, poultry and meat products, sausages, food ingredients or fillings, meat by-products bread, pies, soups, tomato sauce, etc. , Dosage: 200mg-400mg/Kg.
(3) In cosmetics, it is safe to add 0.15% ELA to mouthwash as a preservative. The concentration of cosmetics (except lip makeup, oral hygiene products and sprays) is 0.4%. The concentration in soap, anti-dandruff shampoo and non-spray deodorant is 0.8%.
● The physical and chemical properties of ELA
Appearance: white powder
Melting point: 50-62℃
Solubility: Easily soluble in water at 20°C, completely soluble in ethanol, propylene glycol and glycerin.
● AK Biotech Product Standard
Compliant with European Standard (EU) No 506/2014
Packing: 500g/bag, 1Kg/bag, 25Kg/bag, all use vacuum packaging
Shelf life: original packaging, protected from light, 2 years.
